Drug intelligence / Profile preview

HLK-0016

Development stage
Preclinical
Lead developer
HLK Pharmacin
Modality
Small Molecules
01

Overview

HLK-0016 is an investigational small molecule formulation of oxymorphone being developed by Shenzhen Pharmacin for the management of pain. Developed via the 505(b)(2) regulatory pathway, HLK-0016 likely utilizes the company's proprietary SpraySol™ technology to optimize the delivery or pharmacokinetic profile of the active ingredient. Oxymorphone is a potent semi-synthetic opioid analgesic that primarily acts as an agonist at the mu-opioid receptors in the central nervous system, providing relief for moderate to severe pain. The program is currently in the early stages of development.

Other names
Oxymorphone formulation
02

Targets

KOR (Kappa opioid receptor)DOR (Opioid Receptor Delta 1)MOR (Mu opioid receptor)

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