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HM-242

Development stage
Unknown
Modality
Small Molecules
Administration
Topical
01

Overview

HM-242 is a **novel synthetic antiseptic and disinfectant agent** classified as a triazine derivative with broad-spectrum **microbicidal activity**. It exhibits rapid and potent antimicrobial effects against a wide variety of **Gram-positive and Gram-negative bacteria**, including multidrug-resistant organisms like methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecalis, as well as yeasts and enveloped viruses (such as influenza and herpes simplex virus)[1][2]. Mechanistically, HM-242 acts primarily on the **cell membrane and cell wall**, causing structural disruption and loss of cell integrity, resulting in rapid microbial killing[2]. It was developed as a new disinfectant, with demonstrated efficacy in vitro and in clinical trials for applications such as **wound cleansing** (e.g., venous leg ulcer)[1][2][3].

Other names
4-octyl-6,6-dimethyl-2-(4-methylbenzyl)-1,6-dihydro-1,3,5-triazine-2,4-diamine
02

Targets

Viral lipid envelope

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