Drug intelligence / Profile preview

HMBD-803

Development stage
Preclinical
Lead developer
Callio Therapeutics
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
01

Overview

HMBD-803 is an **antibody-drug conjugate (ADC)** developed by Hummingbird Bioscience Pte Ltd. and currently licensed to Callio Therapeutics. It is in the **preclinical** phase of development. The drug targets an undisclosed antigen and is designed to trigger target internalization. It employs a dual-payload strategy, which is a recent trend in ADC development aimed at overcoming payload resistance.

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