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HN2401
- Development stage
- Preclinical
- Lead developer
- MagicRNA Biotechnology
- Modality
- mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
01
Overview
HN2401 is an investigational mRNA-based therapeutic being developed by MagicRNA for the treatment of autoimmune diseases, specifically Multiple Sclerosis (MS) and Rheumatoid Arthritis (RA). The drug candidate utilizes MagicRNA's proprietary EnC-LNP (Endogenous cell-targeting Lipid Nanoparticle) technology to deliver mRNA designed for immunomodulation. By leveraging the EnC-LNP platform, HN2401 aims to achieve targeted delivery of mRNA to specific immune cells in vivo, potentially restoring immune tolerance or modulating inflammatory pathways. As of early 2024, the program is in the discovery stage, and the specific molecular targets or mRNA sequences have not been publicly disclosed.
- Other names
- HN2401-MagicRNA-mRNA-EnC-LNPHN-2401-MagicRNA-mRNA-EnC-LNPHN 2401-MagicRNA-mRNA-EnC-LNP
02
Targets
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