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hollow gold and silver alloy cuprous oxide shell nano-shell hydrogel
- Development stage
- Unknown
- Lead developer
- Second Affiliated Hospital of Zhejiang University School of Medicine
- Modality
- Nanoparticles → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
- Administration
- Ophthalmic
01
Overview
Hollow gold and silver alloy cuprous oxide shell nano-shell hydrogel is an investigational ophthalmic Au-Ag-Cu2O composite nanogel for severe drug-resistant microbial keratitis. The hydrogel is applied to the corneal ulcer surface and used with 808 nm near-infrared photothermal therapy; irradiation is intended to generate heat and promote release of antimicrobial silver ions, copper ions, and reactive oxygen species. It is being evaluated in an early-phase clinical study sponsored by the Second Affiliated Hospital of Zhejiang University School of Medicine. ([clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05268718))
- Other names
- Au-Ag-Cu2O composite nanogelAu-Ag-Cu-2O composite nanogelAu-Ag-Cu 2O composite nanogelAu-Ag-Cu2O NGAu-Ag-Cu-2O NGAu-Ag-Cu 2O NGgold-silver-cuprous oxide composite nanogelhollow gold and silver alloy cuprous oxide shell nano-shell hydrogel
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