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Homeodent
- Development stage
- Unknown
- Lead developer
- Boiron
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Topical
01
Overview
Homeodent is a phytopharmaceutical mouthwash preparation developed by Boiron, primarily evaluated for the prevention and treatment of oral mucositis in patients undergoing radiotherapy for head and neck cancers. It is a botanical-based formulation typically containing extracts such as *Calendula officinalis*, *Hamamelis virginiana*, *Plantago major*, and *Cochlearia armoracia*. These ingredients are traditionally used for their anti-inflammatory, antiseptic, and healing properties. In clinical trials, it has been compared against standard care (such as sodium bicarbonate mouthwash) to assess its efficacy in reducing the incidence of severe (Grade 3 or higher) radiation-induced oral mucositis.
- Brand names
- Homeodent
- Other names
- Homeodent mouthwash
02
Targets
F-ATPase (Bacterial F-ATPase)ENO (Alpha-enolase)
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