Drug intelligence / Profile preview

Hong Jing Qi Wei

Development stage
Unknown
Lead developer
Xiyuan Hospital
Modality
Small Molecules
Administration
Oral
01

Overview

Hong Jing Qi Wei is a Traditional Chinese Medicine (TCM) formula developed by Xiyuan Hospital of the Chinese Academy of Chinese Medical Sciences, specifically designed to treat type 2 diabetes mellitus and its associated complication, diabetic erectile dysfunction (DED). The formula is centered around *Rhodiola rosea* (Hongjing Tian) and is typically administered as an oral hospital preparation. Its therapeutic effects are mediated through the enhancement of the nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the corpus cavernosum, which facilitates smooth muscle relaxation and improved blood flow. Additionally, it exhibits potent antioxidant properties and inhibits the formation of advanced glycation end-products (AGEs), thereby protecting vascular and neural tissues from chronic hyperglycemic damage. Clinical research at Xiyuan Hospital has demonstrated its efficacy in improving erectile function scores and metabolic parameters in diabetic patients.

Brand names
Hong Jing Qi Wei
Other names
Rhodiola Seven-Flavor FormulaHongjing QiweiHongjing Qiwei SanHongjing Qiwei Wan
02

Targets

NOS1 (nNOS)

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