Drug intelligence / Profile preview

Hongai Tongluo decoction

Development stage: Preclinical
Lead developer: Longhua Hospital Shanghai University of Traditional Chinese Medicine
Administration: Oral

Overview

Hongai Tongluo decoction is a traditional Chinese medicine (TCM) herbal formula used in clinical practice, particularly in China. It is being investigated for its potential to alleviate neurotoxicity induced by oxaliplatin chemotherapy in patients with digestive tract tumors such as gastric and colorectal cancer. The formula is typically administered orally and may be combined with other TCM therapies like Du moxibustion. While the precise herbal composition and mechanism of action are not detailed in the available sources, TCM formulas named "Tongluo" generally aim to promote blood circulation, remove blood stasis, and unblock meridians according to TCM theory. These actions are believed to help reduce symptoms related to nerve injury or toxicity.

Other names: Hongai Tongluo decoction

Targets

MMP9 (Matrix metalloproteinase-9)EGFR T790M (Epidermal growth factor receptor T790M mutant)MAPK3 (Mitogen-activated protein kinase 1)IL-6 (Interleukin 6)NFKBIA (NFKB inhibitor alpha)

Beyond the preview

Go deeper on Hongai Tongluo decoction.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Hongai Tongluo decoction.

Explore the full profile