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Honghe Fujie Xiye is a topical gynecological preparation primarily used for the treatment of vaginitis, including fungal (Candida albicans) and bacterial vaginitis. It is formulated as a vaginal irrigation solution or lotion. The main active ingredient is hawthorn kernel dry distillation liquid, which exhibits anti-inflammatory, antipruritic (anti-itch), antibacterial, and antifungal properties. Pharmacological studies indicate that it can inhibit the growth of Candida albicans and various bacteria in vitro. Mechanistically, it enhances local immune function by promoting macrophage phagocytosis and natural killer cell activity in the vaginal mucosa. It also modulates inflammatory cytokines such as TNF-α and IL-6 to reduce inflammation[1][2]. Clinical research supports its efficacy in relieving symptoms like itching and inflammation associated with vaginitis[2][4][5].
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