Drug intelligence / Profile preview

Honghefujie Lotion

Development stage
Phase 4
Lead developer
Buchang Pharmaceuticals
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Vaginal, Topical
01

Overview

Honghefujie Lotion is a Traditional Chinese Medicine (TCM) botanical drug developed and manufactured by Shanxi Buchang Pharmaceutical. It is formulated as a topical solution derived from the extract of the mature kernels (seeds) of *Crataegus pinnatifida* (hawthorn). The product is primarily indicated for the treatment of various gynecological inflammatory conditions, including vulvovaginal candidiasis and non-specific vaginitis. Its therapeutic effects are attributed to its broad-spectrum antimicrobial activity against pathogens such as *Candida albicans*, as well as its anti-inflammatory and antipruritic properties. The lotion is applied externally or as a vaginal wash to alleviate symptoms such as itching, leucorrhea, and local redness by inhibiting pathogen growth and restoring vaginal microecological balance.

Brand names
Honghefujie Lotion红核妇洁洗液
Other names
Honghe Fujie XiyeRed Kernel Women's Cleansing LotionHonghefujie Wash
02

Targets

Prostaglandin-endoperoxide synthase 1 and 2EGFR T790M (Epidermal growth factor receptor T790M mutant)

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