Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
honghua xiaoyao
- Development stage
- Unknown
- Lead developer
- Lianxin Wang
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Honghua Xiaoyao is a Traditional Chinese Medicine (TCM) botanical formulation used for the treatment of gynecological disorders, specifically premenstrual syndrome (PMS) and menstrual irregularities. It is a derivative of the classic Xiaoyao San formula, enriched with *Carthamus tinctorius* (Honghua) to enhance its blood-circulating and stasis-resolving properties. The formulation typically includes herbs such as *Angelica sinensis*, *Paeonia lactiflora*, and *Bupleurum chinense*. It is primarily indicated for Liver Qi stagnation and Blood deficiency in TCM diagnostics, which clinically manifests as emotional instability, breast tenderness, and abdominal pain associated with the menstrual cycle. Recent clinical research has utilized target trial emulation (TTE) frameworks to evaluate its real-world efficacy and safety compared to standard interventions.
- Brand names
- Honghua Xiaoyao
- Other names
- Honghua Xiaoyao TabletHonghua Xiaoyao WanHonghua Xiaoyao Granules
02
Targets
CYP19A1 (Aromatase)SENP1 (Sentrin-specific protease 1)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)UBE2I (Ubiquitin-conjugating enzyme E2 I)GSK3 (Glycogen synthase kinase 3 beta)ESR1 (ERα)GR (Glucocorticoid receptor)NR5A1 (Steroidogenic factor 1)
Beyond the preview
Go deeper on honghua xiaoyao.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on honghua xiaoyao.