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honghua yellow pigment capsule
- Development stage
- Unknown
- Lead developer
- Shandong Province Natural Medicine Engineering Technology Research Center
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Honghua yellow pigment capsule is a botanical drug product derived from the dried flowers of the safflower plant (*Carthamus tinctorius* L.), developed by the Shandong Province Natural Medicine Engineering Technology Research Center. Its primary active constituent is Hydroxysafflor Yellow A (HSYA), a water-soluble chalcone glycoside. The drug is investigated for the treatment of ischemic stroke (cerebral infarction) during the convalescent phase, specifically targeting patients with the Traditional Chinese Medicine pattern of blood stasis obstructing collaterals. Pharmacologically, it exhibits anti-platelet, anti-thrombotic, and neuroprotective properties. It works by inhibiting platelet aggregation, reducing ischemia-reperfusion injury, and providing antioxidant effects, which collectively help to improve cerebral microcirculation and support neuronal recovery following an ischemic event.
- Other names
- Safflor yellow capsuleHydroxysafflor yellow A capsuleHonghua yellow pigment capsules
02
Targets
PTAFR (Platelet-activating factor receptor)
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