Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Hop flower powder is a botanical preparation derived from the dried strobiles of the *Humulus lupulus* plant. It is widely used in traditional medicine and as a dietary supplement for its sedative, anxiolytic, and estrogenic properties. The pharmacological activity is attributed to a complex mixture of secondary metabolites, including bitter acids (humulones and lupulones), volatile oils (such as myrcene and humulene), and prenylated flavonoids. Notably, the flavonoid 8-prenylnaringenin is recognized as one of the most potent known phytoestrogens, contributing to the use of hops in managing menopausal symptoms like hot flashes. The sedative effects are believed to result from the modulation of the GABAergic system, potentially through the degradation of bitter acids into 2-methyl-3-buten-2-ol, which enhances GABA-A receptor activity. Hops are frequently formulated in combination with other sedative herbs, such as valerian, to treat sleep disorders and restlessness.
Beyond the preview
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Follow clinical development from study design and recruitment through results.
Explore development by indication, patient population, and geography.
Trace asset ownership, licensing agreements, and commercial partnerships.
Explore the patent landscape and regulatory exclusivity around an asset.
Compare development programs by target, modality, and indication.
Connect source evidence and development news to your research questions.
See how Gosset can support your research on hop flower powder.