Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
hormophysa triquerta polyphenol
- Development stage
- Preclinical
- Lead developer
- University of Oklahoma Health Sciences Center
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Hormophysa triquerta polyphenol, specifically the ethyl acetate extract (HT-EA), is a botanical compound derived from the brown seaweed *Hormophysa triquerta*. Developed through research at the University of Oklahoma Health Sciences Center and Annamalai University, it is being investigated for its potential to treat radiotherapy-resistant pancreatic cancer. The extract works by downregulating a broad array of molecules involved in tumor invasion and metastasis, most notably CXCR4 and COX2, as well as beta-catenin and MMP9. By suppressing these targets, HT-EA inhibits the migration and invasion of residual cancer cells that survive clinical radiation, thereby potentially preventing tumor recurrence and metastatic spread.
- Other names
- Hormophysa triquerta ethyl acetate extract
02
Targets
MMP9 (Matrix metalloproteinase-9)CXCR4 (C-X-C motif chemokine receptor 4)CTNNB1 (Beta-catenin)
Beyond the preview
Go deeper on hormophysa triquerta polyphenol.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on hormophysa triquerta polyphenol.