house dust mite allergen

House dust mite (HDM) allergen is a biological extract derived from mites such as *Dermatophagoides pteronyssinus* or *Dermatophagoides farinae*. In clinical research settings, such as those led by the Fraunhofer-Institute of Toxicology and Experimental Medicine, it is utilized as an investigational challenge agent rather than a therapeutic drug. The allergen is typically aerosolized in a controlled Allergen Challenge Chamber (ACC) to induce standardized IgE-mediated allergic responses in sensitized patients. This model is used to study the immunological and clinical skin responses in conditions like atopic dermatitis and allergic rhinitis, facilitating the development of new therapies by providing a reproducible environment for allergen exposure. The specific extract used in the Fraunhofer studies is sourced from ALK-Abello as a lyophilized SQ503 Der p preparation.

Other names

HDM allergenDermatophagoides pteronyssinus allergen extractDer pALK lyophilised SQ503 Der p