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House dust mite allergen extract (Roxall Medizin)
- Development stage
- Unknown
- Lead developer
- Roxall Medizin
- Administration
- Sublingual
01
Overview
House dust mite allergen extract (Roxall Medizin) is a biological product developed for sublingual immunotherapy (SLIT) to treat perennial allergic rhinitis caused by house dust mites (*Dermatophagoides pteronyssinus* and *Dermatophagoides farinae*). The extract is administered sublingually to induce desensitization and immunological tolerance. It works by shifting the immune response from a pro-allergic Th2 profile toward a Th1 and regulatory T-cell (Treg) response, leading to the production of allergen-specific IgG4 antibodies and a reduction in IgE-mediated allergic inflammation. This desensitization process aims to provide long-term relief from symptoms such as sneezing, rhinorrhea, and nasal congestion, while reducing the patient's reliance on symptomatic medications.
- Brand names
- MyrevaRoxall SLIT
- Other names
- House dust mite allergen extractHDM SLITAllergen-Extrakt Roxall
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