Drug intelligence / Profile preview

house dust mite allergen extract (Stallergenes Greer)

Development stage
Unknown
Lead developer
Stallergenes Greer
Modality
Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Sublingual
01

Overview

Staloral 300 acari is a standardized aqueous sublingual immunotherapy (SLIT) solution developed by Stallergenes Greer. It contains a 1:1 mixture of allergen extracts from the house dust mites *Dermatophagoides pteronyssinus* and *Dermatophagoides farinae*, standardized to a concentration of 300 Index of Reactivity (IR). The therapy is indicated for the treatment of house dust mite-induced allergic rhinitis and allergic asthma (including extrinsic/allergic asthma). It works by modulating the immune system to induce allergen-specific tolerance, specifically by reducing the production of allergen-specific IgE and shifting the immune response away from a Th2-mediated allergic profile toward a regulatory T-cell response. It is administered sublingually via a minipump-predosed actuator, allowing for convenient at-home administration.

Brand names
Staloral 300 acariStaloral300 acariStaloral-300 acariStaloral
Other names
Staloral 300Staloral300Staloral-300300 IR house dust mite sublingual solutionDermatophagoides pteronyssinus and Dermatophagoides farinae allergen extract
02

Targets

TCR (T cell antigen receptor complex)

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