Drug intelligence / Profile preview

Houtou Jianweiling

Development stage
Phase 2
Lead developer
Hunan Xinhui Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Houtou Jianweiling is a traditional herbal medicine formulation, primarily derived from the *Hericium erinaceus* (Lion's Mane) mushroom, used for the treatment of various gastrointestinal disorders. It is specifically utilized for chronic non-atrophic gastritis due to its purported ability to promote the repair and regeneration of the gastric mucosa, exert anti-inflammatory effects, and provide cytoprotection against gastric acid and pepsin. The University of Karachi has sponsored clinical research to evaluate its efficacy and safety in a randomized, double-blind, non-inferiority trial comparing it to the proton pump inhibitor omeprazole. The active constituents, including polysaccharides and diterpenoids like erinacines, are thought to modulate inflammatory cytokines and enhance mucosal barrier function.

Brand names
Houtou Jianweiling
Other names
Hericium erinaceus tabletMonkey Head Mushroom tabletHoutou Jianweiling tablet

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