houttuynia cordata water-soluble extract

Houttuynia cordata water-soluble extract is a preparation derived from the leaves of the perennial herb Houttuynia cordata using hot water extraction methods. It contains a range of bioactive compounds including polyphenolic flavonoids (such as quercetin, quercitrin, hyperoside, and rutin) and polysaccharides (notably galacturonic acid, galactose, rhamnose, arabinose). The extract exhibits immunomodulatory, anti-inflammatory, antioxidant, antimicrobial/antibacterial and anti-allergic properties. Mechanistically it modulates inflammatory pathways (including downregulation of NF-κB and MCP-1), supports healthy gut microbiota balance (potentially improving glucose metabolism), protects against oxidative stress in organs such as kidney and heart by reducing inflammatory mediators and reactive oxygen species generation via MAPK/NF-κB signaling inhibition. In dermatological applications it has shown efficacy in suppressing IgE production and Th2 cytokine expression while promoting Th1 responses in atopic dermatitis models[1][3][4][8]. It is used traditionally for infections (including viral), inflammation-related conditions such as interstitial cystitis or skin allergies/eczema[1][3], kidney protection[4], digestive health[1], immune support[2] and has been investigated for hand-foot-mouth disease virus prevention/treatment[5][6].

Other names

houttuynia cordata extractHCWSEHouttuynia cordata water extractH. cordata water extract