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HP-802-247
- Development stage
- Phase 3
- Lead developer
- Smith & Nephew
- Modality
- Cell Therapies, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Devices → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
- Administration
- Topical
01
Overview
HP-802-247 is a cell-based combination product designed for the treatment of chronic wounds, particularly venous leg ulcers. It consists of a fibrinogen solution and a cell preparation containing allogeneic, non-proliferating, living human keratinocytes and fibroblasts delivered in a fibrin matrix by spray application. The mechanism of action involves the release of various growth and angiogenic factors from these metabolically active cells into the wound microenvironment, which stimulates the patient’s own cells to promote healing. Developed as an advanced tissue engineering therapy, it was evaluated in multiple clinical trials for efficacy and safety in chronic venous leg ulcers. The developer/manufacturer is Healthpoint Biotherapeutics.
- Other names
- topical wound spray HP802-247
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