Drug intelligence / Profile preview

HPIV2 vaccine

Development stage
Preclinical
Lead developer
National Institute of Allergy and Infectious Diseases
Modality
Vaccines & Immunotherapeutics
Administration
Intranasal, Intramuscular
01

Overview

The HPIV2 vaccine is a candidate or investigational immunization designed to protect against infection by human parainfluenza virus type 2 (HPIV-2), a common cause of respiratory illnesses such as croup, bronchiolitis, and pneumonia in children. The mechanism of action involves stimulating the immune system to produce antibodies and cellular responses that target HPIV-2, thereby preventing infection or reducing disease severity upon exposure. As of now, there is no licensed or widely available commercial HPIV-2 vaccine; most efforts are in preclinical or early clinical development stages. The primary indication would be prevention of respiratory tract infections caused by HPIV-2.

Other names
human parainfluenza virus type 2 vaccineparainfluenza type 2 vaccine
02

Targets

HPIV2 F/HN (Human parainfluenza virus type 2 fusion glycoprotein and hemagglutinin-neuraminidase glycoprotein)

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