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HR18042 is an investigational small molecule drug developed for the management of moderate to severe acute pain, particularly postoperative pain. It is being evaluated as an oral agent and has reached Phase 2 clinical trials for postoperative analgesia after impacted teeth removal surgery. The drug is classified as a COX-2 inhibitor, suggesting its mechanism involves selective inhibition of the cyclooxygenase-2 enzyme, which plays a key role in inflammation and pain signaling pathways. The developer of HR18042 is Jiangsu Hengrui Medicine.
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