Drug intelligence / Profile preview

HR18042

Development stage
Phase 2
Lead developer
Jiangsu Hengrui Medicine
Modality
Small Molecules
Administration
Oral
01

Overview

HR18042 is an investigational small molecule drug developed for the management of moderate to severe acute pain, particularly postoperative pain. It is being evaluated as an oral agent and has reached Phase 2 clinical trials for postoperative analgesia after impacted teeth removal surgery. The drug is classified as a COX-2 inhibitor, suggesting its mechanism involves selective inhibition of the cyclooxygenase-2 enzyme, which plays a key role in inflammation and pain signaling pathways. The developer of HR18042 is Jiangsu Hengrui Medicine.

02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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