Drug intelligence / Profile preview

hrs-2189

Development stage
Phase 2
Lead developer
Shandong Suncadia Medicine
Modality
Small Molecules
Administration
Oral
01

Overview

HRS-2189 is an orally administered small molecule antineoplastic drug under development by Shandong Suncadia Medicine for the treatment of advanced malignant solid tumors, including breast cancer and prostate cancer. It is being evaluated as a monotherapy and in combination with other investigational agents (such as fluvastatin, fulvestrant, HRS-6209, HRS-8080, and HRS-1358) in multiple phase I/II clinical trials targeting patients with advanced unresectable or metastatic disease. The precise mechanism of action has not been publicly disclosed. Clinical studies are ongoing in China for indications such as breast cancer (including late-stage/metastatic/inoperable cases) and metastatic prostate cancer[2][3][5][7].

02

Targets

DNA-PK (DNA-dependent protein kinase)

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