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HS-10582
- Development stage
- Phase 1
- Lead developer
- Hansoh Pharmaceutical Group
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
HS-10582 is an investigational oral small molecule inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) developed by Jiangsu Hansoh Pharmaceutical. It is designed for the treatment of dyslipidemia, specifically targeting the reduction of low-density lipoprotein cholesterol (LDL-C). By inhibiting PCSK9, the drug prevents the degradation of LDL receptors on the surface of liver cells, thereby increasing the clearance of LDL-C from the bloodstream. As an oral agent, HS-10582 aims to provide a more convenient alternative to the injectable PCSK9 monoclonal antibodies currently on the market. It is currently in Phase I clinical development to evaluate its safety, tolerability, and pharmacokinetics in healthy subjects and patients with mildly elevated LDL-C.
- Other names
- HS-10582HS10582HS 10582
02
Targets
PCSK9 (Proprotein convertase subtilisin/kexin type 9)
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