HS-201

HS-201 is a heat shock protein 90 (HSP90)-targeted photosensitizer developed for photodynamic therapy (PDT) in cancer treatment. It consists of a small molecule HSP90 inhibitor chemically linked to verteporfin, a photosensitizer. By exploiting the high expression of HSP90 in cancer cells, HS-201 selectively accumulates in tumors, enabling targeted visualization and photodynamic therapy. Upon activation by near-infrared light, it generates reactive oxygen species (ROS) to destroy tumor cells while minimizing damage to normal tissue.

Other names

Hsp90-targeted photodynamic therapy agentHsp-90-targeted photodynamic therapy agentHsp 90-targeted photodynamic therapy agentHsp90-targeted photosensitizerHsp-90-targeted photosensitizerHsp 90-targeted photosensitizerverteporfin-Hsp90 inhibitor conjugateverteporfin-Hsp-90 inhibitor conjugateverteporfin-Hsp 90 inhibitor conjugate