Drug intelligence / Profile preview

HT426

Development stage
Unknown
Lead developer
NeuMed Biotechnology
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

HT426 is a standardized botanical extract derived from the fruit peduncles of *Hovenia dulcis* (Oriental Raisin Tree), developed by the South Korean company **Neumed**. It is recognized by the **Ministry of Food and Drug Safety (MFDS)** of South Korea as a functional ingredient for liver health. The extract is primarily utilized for its hepatoprotective properties, specifically its ability to mitigate liver damage caused by alcohol consumption and to support overall hepatic function. HT426 is commonly incorporated into functional foods, beverages, and dietary supplements aimed at fatigue recovery and liver protection, leveraging its ability to enhance the metabolism of alcohol and its toxic byproduct, acetaldehyde.

Other names
Hovenia dulcis fruit peduncle extractOriental Raisin Tree extract헛개나무과병추출분말
02

Targets

ALDH1A1 (Aldehyde dehydrogenase 1 family member A1)ADH (Alcohol dehydrogenase family)

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