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Hua Tan Qu Shi decoction is a Traditional Chinese Medicine (TCM) herbal formula developed by researchers at the Beijing University of Chinese Medicine. It is specifically designed to treat individuals with a phlegm-dampness constitution, a TCM diagnostic phenotype characterized by impaired fluid metabolism and associated with an increased risk of metabolic disorders such as obesity, insulin resistance, and dyslipidemia. The therapeutic rationale for the decoction involves transforming phlegm and expelling dampness to restore metabolic balance. Clinical research, including the GUT-PD-BH-PDC study (ChiCTR1900020674), focuses on the formula's ability to modulate the gut microbiota as a primary mechanism for improving glycemic control in prediabetes and lowering lipid levels in borderline hyperlipidemia.
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