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Hualan Bio Quadrivalent Influenza Vaccine
- Development stage
- Unknown
- Lead developer
- Hualan Biological Bacterin
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
The Hualan Bio Quadrivalent Influenza Vaccine is an inactivated, split-virion vaccine developed by Hualan Biological Bacterin for the prevention of seasonal influenza. It is formulated to contain 15 μg of hemagglutinin (HA) antigen from each of four influenza virus strains: two influenza A subtypes (H1N1 and H3N2) and two influenza B lineages (Yamagata and Victoria). Produced using embryonated chicken eggs, the vaccine is purified and chemically inactivated. It was licensed in China in 2019 and is indicated for active immunization in individuals aged 3 years and older. Clinical evaluations, including Phase IV trials, have demonstrated its safety, immunogenicity, and consistency across different manufacturing batches and age groups.
- Other names
- influenza virus vaccine-Hualan Biological Bacterin Co. Ltd.-Influenzaquadrivalent influenza vaccine (split virion)Hualan Bio IIV4Hualan Bio Quadrivalent Influenza Split-Virion Vaccine
02
Targets
HA (Hemagglutinin)
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