Drug intelligence / Profile preview

huang-long zhi-xiao granule

Development stage
Unknown
Lead developer
Nanjing Huanglong Biotechnology
Modality
Small Molecules
Administration
Oral
01

Overview

Huang-long zhi-xiao granule is a traditional Chinese patent medicine formulation primarily used for the treatment of attention deficit hyperactivity disorder (ADHD) in children. It is also known as Xiaoer Huanglong Granule and HL Granule. The formula consists of multiple herbal ingredients and is widely used in China for pediatric ADHD management, with clinical studies suggesting an effective rate above 80%[1][2][5]. Some related formulations under the "Huanglong" name are also studied for respiratory diseases such as acute asthma, where they have demonstrated anti-inflammatory effects and modulation of lipid metabolism pathways[3][4]. The precise mechanism of action remains unclear but may involve immunomodulation and regulation of inflammatory mediators. The product is developed by Nanjing Huanglong Biotechnology Co., Ltd., a subsidiary of Xinjiang Baihuacun Pharmaceutical Group Co., Ltd.[6].

Brand names
huang-long zhi-xiao granule
Other names
Xiaoer Huanglong GranuleHL GranuleHuanglong Antitussive Granule
02

Targets

IL1B (Interleukin-1 beta)VEGFA (Vascular endothelial growth factor A)GABA-B (Gamma-aminobutyric acid receptor type B)ESR1 (ERα)EGFR T790M (Epidermal growth factor receptor T790M mutant)

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