Drug intelligence / Profile preview

Huangbai Capsule

Development stage
Unknown
Lead developer
Guangdong Xinfeng Pharmaceutical Industry
Modality
Small Molecules
Administration
Oral
01

Overview

Huangbai Capsule is a traditional Chinese medicine (TCM) herbal product developed and manufactured by Guangdong Xinfeng Pharmaceutical. The primary active ingredient is Phellodendron bark (*Phellodendron chinense* or *Phellodendron amurense*), known as Huangbai in TCM. It is formulated as an oral capsule containing yellow powder derived from the herbal material. According to TCM principles, it functions to clear heat, dry dampness, purge fire, and detoxify. It is clinically indicated for a variety of conditions associated with 'damp-heat' and 'fire-toxicity,' including dysentery, jaundice, vaginal discharge, urinary tract infections (hot strangury), and skin conditions such as eczema and carbuncles. Pharmacologically, Phellodendron extracts have demonstrated broad-spectrum antimicrobial activity against various pathogenic bacteria, including *Staphylococcus aureus*, *Salmonella typhi*, and *Mycobacterium tuberculosis*, as well as certain fungi.

Brand names
Huangbai Capsule黄柏胶囊
Other names
黄柏胶囊Huangbai JiaonangPhellodendron bark capsule
02

Targets

NF-κBAKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)MAPK14 (p38 mitogen-activated protein kinase alpha)TLR4 (Toll-like receptor 4)

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