Drug intelligence / Profile preview

Huange Capsule

Development stage
Unknown
Lead developer
Second Affiliated Hospital of Zhejiang University School of Medicine
Administration
Oral
01

Overview

Huange Capsule is a traditional Chinese medicine (TCM) botanical drug product primarily investigated for the treatment of prostatitis, specifically in patients presenting with elevated prostate-specific antigen (PSA) levels (typically 4-10 ng/mL). The formulation is believed to be derived from a combination of herbal extracts, such as *Phellodendron* and *Curcuma* (zedoary), which are thought to provide anti-inflammatory and anti-proliferative activities. It is used as an adjunct to conventional therapy to improve clinical symptoms and reduce serum PSA levels, thereby helping to differentiate between inflammatory conditions and prostate cancer and potentially avoiding unnecessary biopsy procedures. The drug is currently being evaluated in clinical trials led by the Second Affiliated Hospital of Zhejiang University School of Medicine.

Brand names
Huange Capsule
Other names
Huang-E CapsuleHuangge Capsule
02

Targets

RHOA (Ras homolog gene family member A)IL-6 (Interleukin 6)ROCK1 (Rho-associated coiled-coil containing protein kinase 1)TNFA (Tumor necrosis factor alpha (soluble))ROCK2 (Rho-associated coiled-coil containing protein kinase 2)

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