Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Huangjing Yangji Formula
- Development stage
- Unknown
- Lead developer
- China Academy of Chinese Medical Sciences
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Huangjing Yangji Formula (also known as Huangjing Yangji Decoction or HJYJD) is a traditional Chinese medicinal (TCM) herbal formula developed by Wangjing Hospital, China Academy of Chinese Medical Sciences, for the treatment of sarcopenia (age-related muscle loss). The formula is a complex botanical preparation comprising eight primary herbal ingredients: *Polygonati rhizoma*, *Codonopsis radix*, *Rehmanniae radix praeparata*, *Angelica sinensis radix*, *Cistanches herba*, *Lycii fructus*, *Poria*, and *Crataegi fructus*. Mechanistically, HJYJD alleviates skeletal muscle aging and mitochondrial dysfunction by activating the Sirtuin 1 (SIRT1) and Activating Transcription Factor 5 (ATF5)-mediated mitochondrial unfolded protein response (UPRmt) pathway. It is currently being evaluated in multicenter clinical trials, often in combination with resistance training, to improve physical function, muscle strength, and body composition in older adults.
- Other names
- Huangjing Yangji DecoctionHJYJD
02
Targets
ATF5SIRT1 (NAD-dependent protein deacetylase sirtuin-1)
Beyond the preview
Go deeper on Huangjing Yangji Formula.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Huangjing Yangji Formula.