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Huangjingjiannao prescription is a Traditional Chinese Medicine (TCM) herbal formula developed by Guang'anmen Hospital for the treatment of vascular mild cognitive impairment (vMCI). The formula is primarily composed of *Polygonatum sibiricum* (Huangjing) and other traditional herbs intended to tonify the kidney and invigorate the brain. It is currently being evaluated in clinical trials (e.g., ChiCTR2200061393) to assess its efficacy compared to donepezil, focusing on cognitive improvement, daily functioning, and changes in brain connectivity and structure as visualized by multimodality MRI.
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