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huangjinsan
- Development stage
- Preclinical
- Administration
- Oral
01
Overview
Huangjinsan is a traditional Chinese medicine herbal formulation used primarily for kidney disorders such as chronic kidney disease. Preclinical research demonstrates that Huangjinsan can restore renal function in adenine-induced chronic kidney disease in model animals, apparently by regulating metabolic profiles. The specific constituents of Huangjinsan are not fully described in the available sources, and it does not correspond to a single active pharmaceutical ingredient but is rather a formulation of multiple herbal substances according to traditional medicine practices. Its precise mechanism of action is not fully characterized, but it is believed to exert renoprotective effects via modulation of metabolic and possibly inflammatory pathways[1][3][5].
- Other names
- huangjinsan
02
Targets
AMPK (Adenosine monophosphate–activated protein kinase)SCD1 (Stearoyl-CoA desaturase 1)SREBP-1 / SREBF1 (SREBP-1)
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