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Huangqi Bushen mixture
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Huangqi Bushen mixture is a Traditional Chinese Medicine (TCM) formula. Its name suggests it contains Huangqi (Astragalus Radix) and other herbs aimed at 'Bushen,' a TCM concept referring to tonifying the kidney. Astragalus Radix, a key component, is known for its immunomodulatory, anti-hyperglycemic, anti-oxidant, anti-aging, anti-inflammatory, anti-viral, anti-tumor, cardioprotective, and anti-diabetic effects. In TCM, Huangqi is classified as a 'Tonic herb for Qi Deficiency' and is believed to target the Lungs and Spleen, playing a role in strengthening the immune system and boosting energy. The 'Bushen' aspect implies a focus on supporting kidney function, which in TCM theory is associated with reproductive health, vitality, and overall well-being. The mixture has been investigated in clinical trials for conditions such as pediatric asthma.
02
Targets
AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)MAPK3 (Mitogen-activated protein kinase 1)NF-κBPIK3R1 (Phosphatidylinositol 4-phosphate 3-kinase regulatory subunit alpha)RORγtSTAT3 (Signal Transducer and Activator of Transcription 3)TLR2 (Toll-like Receptor 2)TLR4 (Toll-like receptor 4)TLR7 (Toll-like receptor 7)
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