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Huashang I Ironing Therapy Formula is a Traditional Chinese Medicine (TCM) herbal preparation developed by Huadong Hospital Affiliated to Fudan University specifically for the treatment of knee osteoarthritis (KOA). The therapy utilizes the "ironing" method (Tàngyù), a traditional external treatment where the herbal formula is heated and applied topically to the affected joint. This approach combines the pharmacological effects of the constituent herbs with thermal stimulation to enhance local blood circulation, alleviate pain, and reduce inflammation. It is typically indicated for patients exhibiting the "cold-dampness" or "blood stasis" patterns according to TCM diagnostic criteria. Clinical observations suggest that the formula helps improve joint function and reduce the expression of pro-inflammatory cytokines in the synovial fluid.
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