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Huashanshen dropping pills
- Development stage
- Phase 4
- Lead developer
- Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Huashanshen dropping pills is a Traditional Chinese Medicine (TCM) pharmaceutical product derived from the root of *Physochlaina infundibularis* (Huashanshen). The formulation is primarily indicated for the treatment of respiratory ailments, including chronic bronchitis and chronic obstructive pulmonary disease (COPD). Its therapeutic efficacy is attributed to the presence of tropane alkaloids, specifically hyoscyamine and scopolamine, which function as muscarinic acetylcholine receptor antagonists. By blocking these receptors in the bronchial smooth muscle, the drug induces bronchodilation and reduces airway secretions, thereby alleviating symptoms of cough and dyspnea. The dropping pill formulation is a solid dispersion technology intended to enhance the solubility and absorption of the active herbal components.
- Brand names
- Huashanshen dropping pills
- Other names
- Huashanshen DiwanPhysochlaina infundibularis dropping pills
02
Targets
mAChR (Muscarinic acetylcholine receptors)Nicotinic Acetylcholine Receptor
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