Huazhong Univ. of Science and Technology AHR compound B19

Huazhong Univ. of Science and Technology AHR compound B19: sourced facts only. name: "Among them, B19 showed low cytotoxicity (>40 μM) and potent AHR agonist activity with an EC50 value of 2.01 nM, which was 14-fold stronger than that of Tapinarof (28.93 nM)." [PMID:40924124]; target: "Among them, B19 showed low cytotoxicity (>40 μM) and potent AHR agonist activity with an EC50 value of 2.01 nM, which was 14-fold stronger than that of Tapinarof (28.93 nM)." [PMID:40924124]; developer: "Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China." [PMID:40924124]; stage: "Upon topical application, B19 significantly ameliorated imiquimod (IMQ)-induced psoriasis-like cutaneous manifestations and repaired the barrier function of skin, concurrently downregulating the expression levels of CD206, CD36, IL-18, and MCP-1." [PMID:40924124]