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Huhuang Jiangtang

Development stage
Unknown
Lead developer
Beijing Shijia Jiushengyuan Pharmaceutical Technology
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Huhuang Jiangtang is a botanical drug candidate, specifically a Traditional Chinese Medicine (TCM) formulation, developed by Beijing Shijia Jiushengyuan Pharmaceutical Technology for the treatment of type 2 diabetes mellitus. The drug is administered orally in capsule form. It has been evaluated in Phase 1 clinical trials in China (e.g., CTR20131793) to assess its safety, tolerability, and preliminary pharmacokinetic profiles in healthy volunteers. Like many TCM products, it is a multi-component mixture intended to regulate blood glucose levels through complex, multi-target interactions, although its specific molecular mechanism of action has not been definitively characterized in public clinical records.

Brand names
Huhuang Jiangtang
Other names
Huhuang Jiangtang Capsule虎黄降糖胶囊
02

Targets

PPARG (Peroxisome proliferator-activated receptor gamma)Sucrase-IsomaltaseINSR (Insulin receptor)

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