Drug intelligence / Profile preview

Huisheng Oral Liquid

Development stage
Phase 4
Lead developer
Chengdu Di'ao Pharmaceutical
Administration
Oral
01

Overview

Huisheng Oral Liquid (HSOS) is a traditional Chinese patent medicine used for the treatment of primary liver and lung cancer. [1, 4] It is derived from two classical prescriptions, 'Biejiajian Wan' from 'Jin Gui Yao Lue' and 'Huisheng Dan' from 'Wan Bing Hui Chun'. [1] The stated functions of the medicine are to eliminate masses (消癥) and resolve blood stasis (化瘀). [1] Pharmacological studies suggest it may interfere with cancer cell DNA synthesis, affect the cell cycle, and induce apoptosis. [1] It is also reported to improve hypercoagulability in tumor patients, reduce the formation of blood clots, and lower levels of the tumor marker VEGF. [1] Clinical studies have investigated its use as an adjunctive therapy for non-small-cell lung cancer (NSCLC), with some research suggesting that treatment for three months or longer is associated with a higher survival rate in patients with stage II-III NSCLC. It is also used in combination with radiotherapy and chemotherapy to potentially enhance efficacy and reduce toxicity. [1, 9] The medicine is a complex mixture of 34 different herbs, including Panax ginseng, Angelica sinensis, and Rheum rhabarbarum. [1]

Brand names
Huisheng Oral Liquid
Other names
Huisheng oral solution回生口服液Hua zheng Hui sheng dan化癥回生口服液
02

Targets

CD44 (CD44 antigen)IL-1R fam (IL-1 receptor family)MMP2 (Matrix metalloproteinase-2)F3 (Tissue factor)VEGFR2 (Vascular endothelial growth factor receptor 2)CCNB1 (Cyclin B1)CDK1 (Cyclin-dependent kinase 1)CDKN1A (Cyclin-dependent kinase inhibitor 1A)DNAMDM2 (Mouse double minute 2 homolog)EGFR (Epidermal growth factor receptor)ERBB2 (Erb-b2 receptor tyrosine kinase 2)IL-6 (Interleukin 6)E2F1 (E2F Transcription Factor 1)VEGFA (Vascular endothelial growth factor A)

Beyond the preview

Go deeper on Huisheng Oral Liquid.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Huisheng Oral Liquid.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call