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human albumin + CryoStor CS10
- Development stage
- Unknown
- Lead developer
- BioLife Solutions
- Modality
- Recombinant Proteins and Enzymes, Small Molecules
- Administration
- Subcutaneous, Local Injection
01
Overview
human albumin + CryoStor CS10 is a specialized cryopreservation and suspension medium used as a vehicle for the delivery of autologous adipose-derived stromal vascular fraction (AD-SVF) cells. Developed by the Centre Hospitalier Universitaire de Toulouse, this combination is specifically utilized in clinical trials for treating systemic sclerosis and refractory ischemic digital ulcers. The medium typically consists of a 4% human albumin solution mixed with CryoStor CS10, a commercial medium containing 10% dimethyl sulfoxide (DMSO). Human albumin serves as a protein stabilizer and maintains oncotic pressure, while the DMSO in CryoStor CS10 acts as a cryoprotectant, preventing the formation of intracellular ice crystals and maintaining cell viability during the preparation and local injection into the patient's digits.
- Other names
- human albumin and CryoStor CS10 mixturealbumin-CryoStor solutionhuman serum albumin + CryoStor CS10
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