human allogeneic hepatic cells

Human allogeneic hepatic cells are viable liver cells (hepatocytes) isolated from the livers of human donors and intended for transplantation into another individual. These cells are used as a form of cell therapy to treat various liver diseases, particularly in cases where whole-organ transplantation is not feasible or available. The mechanism involves engraftment and functional integration of the transplanted hepatocytes into the recipient's liver, providing metabolic support or replacing deficient enzymatic activity. This approach is being explored for acute liver failure, inherited metabolic disorders affecting the liver, and other severe hepatic conditions[2][3]. The primary therapeutic effect comes from restoring lost or deficient hepatic functions through direct cellular replacement.

Other names

human allogeneic hepatocytesdonor-derived human liver cells