human amniotic mesenchymal stem cells

Human amniotic mesenchymal stem cells (hAMSCs) are a type of stem cell therapy derived from the mesenchymal layer of the human amniotic membrane. These cells have gained significant attention in regenerative medicine due to their unique properties and therapeutic potential. ## Description Human amniotic mesenchymal stem cells (hAMSCs) are pluripotent stem cells isolated from the fibroblastic layer of the human amniotic membrane, typically obtained from placentas after elective cesarean sections. These cells possess several advantageous characteristics that make them promising candidates for cell-based therapies: - **Low immunogenicity**: hAMSCs exhibit minimal immune rejection when transplanted - **Potent paracrine functions**: They secrete various bioactive factors that promote tissue regeneration - **Immunomodulatory properties**: They can regulate immune responses and suppress inflammation - **No tumorigenicity**: Unlike some other stem cell types, hAMSCs do not form tumors when transplanted - **Ethical advantages**: Their collection from discarded placental tissue avoids ethical concerns hAMSCs have demonstrated therapeutic potential in promoting bone regeneration, treating joint diseases, addressing neurological disorders, and managing various inflammatory conditions through their ability to modulate inflammation, promote angiogenesis, inhibit oxidative stress, induce neurogenesis, and stimulate remyelination[1][2][4].

Other names

hAMSCs