Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
human embryonic stem cell-derived retinal pigment epithelium cells
- Development stage
- Unknown
- Lead developer
- Beijing Institute of Zoology
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Ophthalmic
01
Overview
Human embryonic stem cell-derived retinal pigment epithelium (hESC-RPE) cells are a cell therapy product designed to treat degenerative retinal diseases such as retinitis pigmentosa and age-related macular degeneration. These cells are differentiated in vitro from pluripotent human embryonic stem cells into functional RPE cells. When transplanted into the subretinal space, they are intended to replace damaged or lost native RPE cells, which are critical for maintaining photoreceptor health through functions such as nutrient transport, light absorption, and the phagocytosis of shed photoreceptor outer segments. The Institute of Zoology at the Chinese Academy of Sciences is investigating these clinical-grade cells in early-phase trials to evaluate their safety and potential to preserve visual function in patients with advanced retinitis pigmentosa.
- Other names
- hESC-derived RPE cellshuman embryonic stem cell-derived RPE cells
Beyond the preview
Go deeper on human embryonic stem cell-derived retinal pigment epithelium cells.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on human embryonic stem cell-derived retinal pigment epithelium cells.