human papillomavirus type 18 L1 protein virus-like particle

Human papillomavirus type 18 L1 protein virus-like particle is a **type-specific prophylactic HPV vaccine antigen** composed of the recombinant major capsid protein L1 from HPV18 that self-assembles into noninfectious virus-like particles. As an L1 VLP immunogen, it is designed to induce neutralizing antibody responses against **human papillomavirus type 18**, thereby preventing new infection rather than clearing established infection. The exact input refers to the **monovalent HPV18 L1 VLP component** rather than a marketed multivalent product such as quadrivalent or bivalent HPV vaccines. Available public evidence supports use of this antigen as a vaccine component studied in prophylactic HPV vaccination programs; the provided association with Institut Gustave Roussy and HSIL appears more consistent with broader HPV vaccine research in secondary prevention settings than with a distinct approved monovalent HPV18 L1 VLP product.

Brand names

GardasilGardasil 9Gardasil9Gardasil-9Cervarix

Other names

HPV18 L1 virus-like particleHPV-18 L1 virus-like particleHPV 18 L1 virus-like particlehuman papillomavirus 18 L1 VLPHPV type 18 L1 VLP