human papillomavirus type 58 L1 protein virus-like particle

Human papillomavirus type 58 L1 protein virus-like particle is a **recombinant HPV58 major capsid protein self-assembled into non-infectious virus-like particles** intended to function as an HPV vaccine antigen. As an L1 VLP vaccine, it is designed to present conformational epitopes that induce **type-specific neutralizing antibody responses against HPV58**, thereby helping prevent infection and HPV58-associated neoplastic disease rather than directly killing infected cells. HPV58 is a high-risk genotype linked to cervical precancer and cancer, with particular epidemiologic importance in East Asia. Based on the name provided and the available context, this entity appears to refer to a **monovalent HPV58 VLP antigen/candidate** rather than an approved commercial product; Institut Gustave Roussy is listed in the provided context as a known developer, and the associated disease context is high-grade squamous intraepithelial lesion related to HPV.

Other names

HPV58 L1 virus-like particleHPV-58 L1 virus-like particleHPV 58 L1 virus-like particlehuman papillomavirus 58 L1 virus-like particlehuman papillomavirus type 58 L1 protein VLP