Drug intelligence / Profile preview

human rabies immunoglobulin

Development stage
Unknown
Lead developer
Tonglu Biopharmaceutical
Modality
Antibody-Based Therapeutics
Administration
Intramuscular, Perilesional
01

Overview

Human rabies immunoglobulin (HRIG) is a plasma-derived biologic developed by Tonglu Biopharmaceutical for the post-exposure prophylaxis of rabies. It consists of a sterile solution of antirabies antibodies concentrated from the plasma of hyperimmunized human donors. HRIG provides immediate passive immunity by binding to and neutralizing the rabies virus at the site of exposure, preventing the virus from attaching to and entering nerve cells. This treatment is critical during the window before a patient's active immune response is triggered by the rabies vaccine. It is typically administered via local infiltration around the wound and intramuscular injection.

Brand names
狂犬病人免疫球蛋白
Other names
狂犬病人免疫球蛋白HRIGHuman Rabies Immunoglobulin
02

Targets

RABV-G (Rabies virus glycoprotein)

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