human relaxin-1

Human relaxin-1 is a synthetic peptide developed by Relaxera that mimics the endogenous human H1 relaxin hormone. It functions as a dual agonist of the relaxin-family peptide receptors RXFP1 and RXFP2. While human relaxin-2 (H2) is the most studied member of the family and the primary circulating form in humans, relaxin-1 is known to be expressed in specific tissues such as the decidua, trophoblast, and prostate, suggesting localized physiological roles. Relaxera's synthetic version is utilized in preclinical research to explore therapeutic potential in areas such as fibrosis, cardiovascular disease, and reproductive health, leveraging the peptide's ability to modulate extracellular matrix metabolism, promote vasodilation, and exert anti-inflammatory effects.

Other names

H1 relaxinH-1 relaxinH 1 relaxinRelaxin-1Relaxin1Relaxin 1