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Drug intelligence / Profile preview
human serum albumin + indocyanine green
- Development stage
- Preclinical
- Modality
- Small Molecules, Recombinant Proteins and Enzymes
- Administration
- Intravenous
01
Overview
This is a combination product consisting of human serum albumin (HSA) and indocyanine green (ICG). Indocyanine green is a near-infrared fluorescent dye that binds to plasma proteins, especially albumin, after intravenous injection. The resulting complex, ICG-HSA, exhibits enhanced tumor-targeting properties compared to free ICG due to the biological characteristics of HSA. This conjugate is primarily used as an imaging probe in biomedical research and clinical diagnostics for real-time tracking of protein distribution, assessment of tissue perfusion, and tumor localization via fluorescence imaging. Mechanistically, the HSA component serves as a carrier that prolongs circulation time and improves targeting efficiency; the ICG component provides strong near-infrared fluorescence for deep-tissue imaging[3][4][8]. The combination does not have direct therapeutic effects but serves as an advanced diagnostic tool.
- Brand names
- ICG-HSA
- Other names
- 吲哚菁绿标记人血清白蛋白人血清白蛋白 + 吲哚菁绿Indocyanine green-labeled human serum albumin
02
Targets
gp60 (GP60 Receptor)SPARC (Secreted protein acidic and rich in cysteine)
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