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human umbilical cord-derived mesenchymal stem cells (Hebei Medical University)
- Development stage
- Unknown
- Lead developer
- Hebei Medical University
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) is an investigational allogeneic cell therapy developed by Hebei Medical University for the treatment of systemic lupus erythematosus (SLE). This biologic modality involves the intravenous administration of mesenchymal stem cells harvested from umbilical cord tissue. The therapeutic mechanism is centered on immunomodulation and metabolic reprogramming; specifically, the cells influence the glucose metabolism pathways of CD4+ T cells to suppress the overactive immune response characteristic of SLE. Clinical research conducted by Hebei Medical University has evaluated the safety and efficacy of these cells in patients with active and refractory disease, often as an adjunct to conventional immunosuppressive therapy.
- Other names
- hUC-MSCsumbilical cord-derived mesenchymal stem cellshUC-MSCs (Hebei)
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